Inadequacies within the African healthcare sector have been of concern for a long time. Nevertheless, the COVID-19 pandemic was a global wake-up call for many, reminding us that we have a shared responsibility to create strong healthcare systems. A large proportion of healthcare funding has been directed towards COVID-19 in the last few years, and this has hampered progress towards integrated care and universal health coverage (UHC). Public debt has increased because of the pandemic, the economic crisis and global political unrest like the war in Ukraine making it even more challenging to finance healthcare. Trust in healthcare systems in sub-Saharan Africa was already low, and the volatile economic situation has exacerbated this. Millions of people are becoming more financially insecure due to high inflation and unexpected medical costs. We believe there are ways to overcome this and build strong healthcare systems. The pandemic provided helpful evidence of the value of digital solutions for healthcare and finance, which is a vital element of UHC. At PharmAccess, we are designing, piloting, and implementing digital solutions to improve people’s access to healthcare, which also strengthens their financial resilience. We are developing evidence-based healthcare solutions for impact, we create partnership and advocate for their adoption at scale. We would like to take this opportunity to thank Her Majesty for her visit to Tanzania in October 2022, where we were able to share with her the positive impact MomCare is having on one of the most vulnerable groups in sub-Saharan Africa: pregnant women in low-income groups. As the pandemic derailed the goal of UHC in Africa, we need greater investment, including from the private sector, and the commitment of national governments to (co-)pay for insurance for low-income groups. PharmAccess is working closely with the private sector to strengthen its involvement. Effective healthcare systems need efficient digital solutions increase reach and enable the better allocation of funds. Importantly, transparency is a vital building block for trust; transparent data will need to be fair and controlled by the user. These are some of the issues we cover in this report, which provides a broad picture of what we are doing, the impact created as well as the challenges we face in our efforts. Many of PharmAccess’ core endeavors are complementary with those of Her Majesty. We are striving for scaling technology to improve quality and safety of healthcare and effectively expand access to insurance for underserved communities, contributing to financial health and inclusion. We therefore look forward to strengthening our collaboration with a follow-up discussion soon.